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Apoferritin improves motor deficits in MPTP-treated mice by regulating brain iron metabolism and ferroptosis
Iron deposition is one of the key factors in the etiology of Parkinson's disease (PD). Iron-free-apoferritin has the ability to store iron by combining with a ferric hydroxide-phosphate compound to form ferritin. In this study, we investigated the role of apoferritin in 1-methyl-4-phenyl-1,2,3,...
Autores principales: | Song, Li-Mei, Xiao, Zhi-Xin, Zhang, Na, Yu, Xiao-Qi, Cui, Wei, Xie, Jun-Xia, Xu, Hua-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105649/ https://www.ncbi.nlm.nih.gov/pubmed/33997705 http://dx.doi.org/10.1016/j.isci.2021.102431 |
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