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Hypochlorous acid-modified human serum albumin suppresses MHC class II - dependent antigen presentation in pro-inflammatory macrophages
Macrophages are innate immune cells that internalize and present exogenous antigens to T cells via MHC class II proteins. They operate at sites of infection in a highly inflammatory environment, generated in part by reactive oxygen species, in particular the strong oxidant hypochlorous acid (HOCl) p...
Autores principales: | Ulfig, Agnes, Bader, Verian, Varatnitskaya, Marharyta, Lupilov, Natalie, Winklhofer, Konstanze F., Leichert, Lars I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105673/ https://www.ncbi.nlm.nih.gov/pubmed/33940547 http://dx.doi.org/10.1016/j.redox.2021.101981 |
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