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Phenotypic analysis of a transgenic Drosophila model of Alzheimer’s amyloid-β toxicity

For decades, the fruit fly Drosophila melanogaster has been an efficient genetic model to investigate many aspects of human neurodegenerative diseases. Through genetic and pharmacologic approaches, these studies have revealed the molecular mechanisms underlying disease pathogenesis and provided ther...

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Detalles Bibliográficos
Autores principales: Sekiya, Michiko, Iijima, Koichi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105684/
https://www.ncbi.nlm.nih.gov/pubmed/33997815
http://dx.doi.org/10.1016/j.xpro.2021.100501