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Unconventional voltage sensing in an inwardly rectifying potassium channel
Inwardly rectifying potassium channels are generally thought to achieve their physiological voltage dependence via an “extrinsic” mechanism involving voltage-dependent block by polyamines. A surprising finding of polyamine-independent gating of Kir4.1/Kir5.1 heteromeric channels suggests a mechanism...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105720/ https://www.ncbi.nlm.nih.gov/pubmed/33956072 http://dx.doi.org/10.1085/jgp.202112929 |