Cargando…
Unconventional voltage sensing in an inwardly rectifying potassium channel
Inwardly rectifying potassium channels are generally thought to achieve their physiological voltage dependence via an “extrinsic” mechanism involving voltage-dependent block by polyamines. A surprising finding of polyamine-independent gating of Kir4.1/Kir5.1 heteromeric channels suggests a mechanism...
Autor principal: | Kurata, Harley T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105720/ https://www.ncbi.nlm.nih.gov/pubmed/33956072 http://dx.doi.org/10.1085/jgp.202112929 |
Ejemplares similares
-
The Polyamine Binding Site in Inward Rectifier K(+) Channels
por: Kurata, Harley T., et al.
Publicado: (2006) -
Gating and modulation of an inward-rectifier potassium channel
por: Jogini, Vishwanath, et al.
Publicado: (2022) -
Inward rectifiers and their regulation by endogenous polyamines
por: Baronas, Victoria A., et al.
Publicado: (2014) -
Spermine Is Fit to Block Inward Rectifier (Kir) Channels
por: Stanfield, Peter R., et al.
Publicado: (2003) -
Long-pore Electrostatics in Inward-rectifier Potassium Channels
por: Robertson, Janice L., et al.
Publicado: (2008)