MyD88 oligomer size functions as a physical threshold to trigger IL1R Myddosome signaling

A recurring feature of innate immune receptor signaling is the self-assembly of signaling proteins into oligomeric complexes. The Myddosome is an oligomeric complex that is required to transmit inflammatory signals from TLR/IL1Rs and consists of MyD88 and IRAK family kinases. However, the molecular...

Descripción completa

Detalles Bibliográficos
Autores principales: Deliz-Aguirre, Rafael, Cao, Fakun, Gerpott, Fenja H.U., Auevechanichkul, Nichanok, Chupanova, Mariam, Mun, YeVin, Ziska, Elke, Taylor, Marcus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105725/
https://www.ncbi.nlm.nih.gov/pubmed/33956941
http://dx.doi.org/10.1083/jcb.202012071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105725/
https://www.ncbi.nlm.nih.gov/pubmed/33956941
http://dx.doi.org/10.1083/jcb.202012071

Ejemplares similares