Loss of EZH2-like or SU(VAR)3–9-like proteins causes simultaneous perturbations in H3K27 and H3K9 tri-methylation and associated developmental defects in the fungus Podospora anserina

BACKGROUND: Selective gene silencing is key to development. It is generally accepted that H3K27me3-enriched heterochromatin maintains transcriptional repression established during early development and regulates cell fate. Conversely, H3K9me3-enriched heterochromatin prevents differentiation but con...

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Detalles Bibliográficos
Autores principales: Carlier, F., Li, M., Maroc, L., Debuchy, R., Souaid, C., Noordermeer, D., Grognet, P., Malagnac, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105982/
https://www.ncbi.nlm.nih.gov/pubmed/33962663
http://dx.doi.org/10.1186/s13072-021-00395-7

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