Cargando…

The clinical significance of remnant thyroid tissue in thyroidectomized differentiated thyroid cancer patients on (131)I-SPECT/CT

BACKGROUND: To explore the (131)I-SPECT/CT characteristics of remnant thyroid tissue (RTT) in differentiated thyroid cancer (DTC), further assess the risk factors and clinical significance. METHODS: 52 DTC patients after total thyroidectomy had undergone neck (131)I-SPECT/CT before (131)I ablation....

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Feng, Nie, Hui, Li, Wei, Zhang, Rusen, Li, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105984/
https://www.ncbi.nlm.nih.gov/pubmed/33964885
http://dx.doi.org/10.1186/s12880-021-00612-5
_version_ 1783689687923163136
author Wang, Feng
Nie, Hui
Li, Wei
Zhang, Rusen
Li, Wen
author_facet Wang, Feng
Nie, Hui
Li, Wei
Zhang, Rusen
Li, Wen
author_sort Wang, Feng
collection PubMed
description BACKGROUND: To explore the (131)I-SPECT/CT characteristics of remnant thyroid tissue (RTT) in differentiated thyroid cancer (DTC), further assess the risk factors and clinical significance. METHODS: 52 DTC patients after total thyroidectomy had undergone neck (131)I-SPECT/CT before (131)I ablation. The diagnosis of RTT was based on SPECT/CT and follow-up at least 3 months. The anatomic locations and features of SPECT/CT of RTT were assessed by reviewers. The risk factors of RTT with CT positive were analyzed by the chi-square test. RESULTS: A total of 80 lesions of RTT were diagnosed in this study, most of them were mainly located in the regions adjacent to trachea cartilage (37/80) or lamina of thyroid cartilage (17/80). On SPECT/CT of RTT, low, moderate and high uptake were respectively noted in 10, 24 and 46 lesions, definite positive, suspected positive and negative CT findings were respectively noted in 10, 21 and 49. The RTT lesions with definite positive CT findings were mainly located adjacent to lamina of thyroid cartilage (5/10). Primary thyroid tumor (P = 0.029) and T stage (P = 0.000) were the effective risk factors of CT positive RTT. CONCLUSIONS: RTT has certain characteristic distribution and appearances on SPECT/CT. Most of RTT with definite CT abnormalities located adjacent to lamina of thyroid cartilage, which suggest surgeons should strengthen the careful removal in this region, especially primary thyroid tumor involving bilateral and T4 stage. This study can provide a certain value for the improvement of thyroidectomy quality in DTC patients.
format Online
Article
Text
id pubmed-8105984
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-81059842021-05-10 The clinical significance of remnant thyroid tissue in thyroidectomized differentiated thyroid cancer patients on (131)I-SPECT/CT Wang, Feng Nie, Hui Li, Wei Zhang, Rusen Li, Wen BMC Med Imaging Research BACKGROUND: To explore the (131)I-SPECT/CT characteristics of remnant thyroid tissue (RTT) in differentiated thyroid cancer (DTC), further assess the risk factors and clinical significance. METHODS: 52 DTC patients after total thyroidectomy had undergone neck (131)I-SPECT/CT before (131)I ablation. The diagnosis of RTT was based on SPECT/CT and follow-up at least 3 months. The anatomic locations and features of SPECT/CT of RTT were assessed by reviewers. The risk factors of RTT with CT positive were analyzed by the chi-square test. RESULTS: A total of 80 lesions of RTT were diagnosed in this study, most of them were mainly located in the regions adjacent to trachea cartilage (37/80) or lamina of thyroid cartilage (17/80). On SPECT/CT of RTT, low, moderate and high uptake were respectively noted in 10, 24 and 46 lesions, definite positive, suspected positive and negative CT findings were respectively noted in 10, 21 and 49. The RTT lesions with definite positive CT findings were mainly located adjacent to lamina of thyroid cartilage (5/10). Primary thyroid tumor (P = 0.029) and T stage (P = 0.000) were the effective risk factors of CT positive RTT. CONCLUSIONS: RTT has certain characteristic distribution and appearances on SPECT/CT. Most of RTT with definite CT abnormalities located adjacent to lamina of thyroid cartilage, which suggest surgeons should strengthen the careful removal in this region, especially primary thyroid tumor involving bilateral and T4 stage. This study can provide a certain value for the improvement of thyroidectomy quality in DTC patients. BioMed Central 2021-05-08 /pmc/articles/PMC8105984/ /pubmed/33964885 http://dx.doi.org/10.1186/s12880-021-00612-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Wang, Feng
Nie, Hui
Li, Wei
Zhang, Rusen
Li, Wen
The clinical significance of remnant thyroid tissue in thyroidectomized differentiated thyroid cancer patients on (131)I-SPECT/CT
title The clinical significance of remnant thyroid tissue in thyroidectomized differentiated thyroid cancer patients on (131)I-SPECT/CT
title_full The clinical significance of remnant thyroid tissue in thyroidectomized differentiated thyroid cancer patients on (131)I-SPECT/CT
title_fullStr The clinical significance of remnant thyroid tissue in thyroidectomized differentiated thyroid cancer patients on (131)I-SPECT/CT
title_full_unstemmed The clinical significance of remnant thyroid tissue in thyroidectomized differentiated thyroid cancer patients on (131)I-SPECT/CT
title_short The clinical significance of remnant thyroid tissue in thyroidectomized differentiated thyroid cancer patients on (131)I-SPECT/CT
title_sort clinical significance of remnant thyroid tissue in thyroidectomized differentiated thyroid cancer patients on (131)i-spect/ct
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105984/
https://www.ncbi.nlm.nih.gov/pubmed/33964885
http://dx.doi.org/10.1186/s12880-021-00612-5
work_keys_str_mv AT wangfeng theclinicalsignificanceofremnantthyroidtissueinthyroidectomizeddifferentiatedthyroidcancerpatientson131ispectct
AT niehui theclinicalsignificanceofremnantthyroidtissueinthyroidectomizeddifferentiatedthyroidcancerpatientson131ispectct
AT liwei theclinicalsignificanceofremnantthyroidtissueinthyroidectomizeddifferentiatedthyroidcancerpatientson131ispectct
AT zhangrusen theclinicalsignificanceofremnantthyroidtissueinthyroidectomizeddifferentiatedthyroidcancerpatientson131ispectct
AT liwen theclinicalsignificanceofremnantthyroidtissueinthyroidectomizeddifferentiatedthyroidcancerpatientson131ispectct
AT wangfeng clinicalsignificanceofremnantthyroidtissueinthyroidectomizeddifferentiatedthyroidcancerpatientson131ispectct
AT niehui clinicalsignificanceofremnantthyroidtissueinthyroidectomizeddifferentiatedthyroidcancerpatientson131ispectct
AT liwei clinicalsignificanceofremnantthyroidtissueinthyroidectomizeddifferentiatedthyroidcancerpatientson131ispectct
AT zhangrusen clinicalsignificanceofremnantthyroidtissueinthyroidectomizeddifferentiatedthyroidcancerpatientson131ispectct
AT liwen clinicalsignificanceofremnantthyroidtissueinthyroidectomizeddifferentiatedthyroidcancerpatientson131ispectct