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Forkhead box O1 targeting replication factor C subunit 2 expression promotes glioma temozolomide resistance and survival

BACKGROUND: Additional mechanisms of temozolomide (TMZ) resistance in gliomas remain uncertain. The aim of this study was to identify another DNA repair mechanism involving forkhead box O1 (FoxO1) and replicator C2 (RFC2) in gliomas. METHODS: We established glioma cells against TMZ, U87R, by exposur...

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Detalles Bibliográficos
Autores principales:	Qiu, Xingsheng, Tan, Guifeng, Wen, Hao, Lian, Lian, Xiao, Songhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105996/ https://www.ncbi.nlm.nih.gov/pubmed/33987390 http://dx.doi.org/10.21037/atm-21-1523

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