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The G199X and V157fs mutations in the TP53 gene promote malignancy in serous ovarian cancer: an analysis using whole-exome sequencing

BACKGROUND: The carcinogenic mechanisms underlying serous ovarian cancer are not fully understood. METHODS: Whole-exome sequencing and targeted sequencing were performed in ovarian cancer samples to identify novel molecular markers involved in the process of cell malignancy in ovarian cancer. In vit...

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Detalles Bibliográficos
Autores principales: Su, Dan, Nie, Man, Yue, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106005/
https://www.ncbi.nlm.nih.gov/pubmed/33987408
http://dx.doi.org/10.21037/atm-21-583

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