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A comprehensive pan-cancer analysis of CD274 gene amplification, tumor mutation burden, microsatellite instability, and PD-L1 expression in Chinese cancer patients

BACKGROUND: Immune checkpoint inhibitors blocking programmed cell death 1 (PD-1) or programmed cell death ligand 1 (PD-L1) have emerged as effective treatment options for cancer. However, immunotherapy is only effective in a subset of patients. Identifying effective biomarkers to predict the treatme...

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Detalles Bibliográficos
Autores principales: Gao, Guanghui, Zhang, Xiao-Dong, Qu, Hu, Yao, Bing, Zhou, Yuxi, Xiang, Jianxing, Chen, Chunxiang, Hou, Ting, Chen, Kai, Xu, Junying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106035/
https://www.ncbi.nlm.nih.gov/pubmed/33987375
http://dx.doi.org/10.21037/atm-21-853