Diabetic nephropathy in mice is aggravated by the absence of podocyte IRE1 and is correlated with reduced kidney ADH1 expression

BACKGROUND: Inositol-requiring enzyme 1 (IRE1) plays a critical role in attenuating endoplasmic reticulum (ER) stress associated with renal injury which may also be a factor in diabetic nephropathy (DN). Alcohol dehydrogenase type I (ADH1) activity is prominent in the kidney, ADH1 activity is also r...

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Detalles Bibliográficos
Autores principales: Xie, Liping, Guo, Kaifeng, Lu, Sijia, Wang, Ning, Wang, Yanping, Chen, Haibing, Liu, Junli, Jia, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106116/
https://www.ncbi.nlm.nih.gov/pubmed/33987334
http://dx.doi.org/10.21037/atm-20-6356

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