Cargando…

HHLA2 predicts better survival and exhibits inhibited proliferation in epithelial ovarian cancer

PURPOSE: The role of HHLA2, a new immune checkpoint ligand, is gradually being elucidated in various solid tumours. However, its role in ovarian cancer remains unclear; thus, its expression profile and clinical significance in ovarian cancer must be examined. METHODS: We performed immunohistochemist...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Guocai, Shi, Yuanyuan, Ling, Xiaoting, Wang, Dongyan, Liu, Yunyun, Lu, Huaiwu, Peng, Yongpai, Zhang, Bingzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106145/ https://www.ncbi.nlm.nih.gov/pubmed/33962626 http://dx.doi.org/10.1186/s12935-021-01930-y

Ejemplares similares

Diagnostic Value of Assessment of Cervical Involvement in Early-Stage Endometrial Adenocarcinoma: Comparison of Magnetic Resonance Imaging (MRI) Versus Hysteroscopy
por: Xu, Guocai, et al.
Publicado: (2018)

Overexpression of HHLA2 in human clear cell renal cell carcinoma is significantly associated with poor survival of the patients
por: Chen, Lujun, et al.
Publicado: (2019)

Galectin-3 and β-catenin are associated with a poor prognosis in serous epithelial ovarian cancer
por: Liu, Yunyun, et al.
Publicado: (2018)

HHLA2 Expression is Associated with Poor Survival in Patients with Hepatocellular Carcinoma
por: Xu, Yituo, et al.
Publicado: (2021)

Low BCL9 expression inhibited ovarian epithelial malignant tumor progression by decreasing proliferation, migration, and increasing apoptosis to cancer cells
por: Wang, Jing, et al.
Publicado: (2019)

KIR3DL3-HHLA2 and TMIGD2-HHLA2 pathways: The dual role of HHLA2 in immune responses and its potential therapeutic approach for cancer immunotherapy
por: Li, Yang, et al.
Publicado: (2022)

HHLA2 is expressed in pancreatic and ampullary cancers and increased expression is associated with better post-surgical prognosis
por: Boor, Patrick P. C., et al.
Publicado: (2020)

CircCASC15-miR-100-mTOR may influence the cervical cancer radioresistance
por: Yao, Tingting, et al.
Publicado: (2022)

Suramin inhibits cell proliferation in ovarian and cervical cancer by downregulating heparanase expression
por: Li, HuaPing, et al.
Publicado: (2015)

Inhibition of human lung cancer cell proliferation and survival by wine
por: Barron, Carly C, et al.
Publicado: (2014)

High-grade serous ovarian cancer cell lines exhibit heterogeneous responses to growth factor stimulation
por: Bourgeois, Danielle L., et al.
Publicado: (2015)

Is Ovarian Preservation Feasible in Early-Stage Adenocarcinoma of the Cervix?
por: Lu, Huaiwu, et al.
Publicado: (2016)

Response to microtubule-interacting agents in primary epithelial ovarian cancer cells
por: Pellicciotta, Ilenia, et al.
Publicado: (2013)

Metformin exhibits the anti-proliferation and anti-invasion effects in hepatocellular carcinoma cells after insufficient radiofrequency ablation
por: Zhang, Qingyun, et al.
Publicado: (2017)

Elevated CA-125 Level and ER-Negative as Prognostic Factors for Ovarian Metastasis in Patients with Endometrial Cancer: A Retrospective Cohort Study
por: Ling, Xiaoting, et al.
Publicado: (2020)

Cyclin H predicts the poor prognosis and promotes the proliferation of ovarian cancer
por: Peng, Chen, et al.
Publicado: (2020)

Ovarian cyst removal influences ovarian reserve dependent on histology, size and type of operation
por: Henes, Melanie, et al.
Publicado: (2018)

Metabolome analysis reveals a diversity of cancer tissues in advanced epithelial ovarian cancer
por: Yoshida, Kosuke, et al.
Publicado: (2021)

B7-H7 (HHLA2) inhibits T-cell activation and proliferation in the presence of TCR and CD28 signaling
por: Rieder, Sadiye Amcaoglu, et al.
Publicado: (2020)

Predictive value of RAD51 on the survival and drug responsiveness of ovarian cancer
por: Feng, Yuchen, et al.
Publicado: (2021)

Regulation of HHLA2 expression in kidney cancer and myeloid cells
por: Shigemura, Tomonari, et al.
Publicado: (2023)

miR-206 as a prognostic and sensitivity biomarker for platinum chemotherapy in epithelial ovarian cancer
por: Yu, Xiaotang, et al.
Publicado: (2020)

Platelet-activating factor acetyl hydrolase IB2 dysregulated cell proliferation in ovarian cancer
por: He, YingYing, et al.
Publicado: (2021)

Downregulated lincRNA HOTAIR expression in ovarian cancer stem cells decreases its tumorgeniesis and metastasis by inhibiting epithelial-mesenchymal transition
por: Wang, Jing, et al.
Publicado: (2015)

RIPK1 polymorphisms and expression levels: impact on genetic susceptibility and clinical outcome of epithelial ovarian cancer
por: Wang, Xuedong, et al.
Publicado: (2023)

Increased cell survival by inhibition of BRCA1 using an antisense approach in an estrogen responsive ovarian carcinoma cell line
por: Annab, Lois A, et al.
Publicado: (2000)

A novel Notch1 missense mutation (C1133Y) in the Abruptex domain exhibits enhanced proliferation and invasion in oral squamous cell carcinoma
por: Zheng, Yang, et al.
Publicado: (2018)

miR-454 suppresses the proliferation and invasion of ovarian cancer by targeting E2F6
por: An, Yunhe, et al.
Publicado: (2020)

SYT7 acts as an oncogene and a potential therapeutic target and was regulated by ΔNp63α in HNSCC
por: Fu, You, et al.
Publicado: (2021)

Better governance, better access: practising responsible data sharing in the METADAC governance infrastructure
por: Murtagh, Madeleine J., et al.
Publicado: (2018)

BRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells
por: Johnson, Nicole C, et al.
Publicado: (2002)

Long-term primary culture of a clear cell ovarian carcinoma reveals an epithelial–mesenchymal cooperative interaction
por: Goyeneche, Alicia A., et al.
Publicado: (2015)

Pentraxin 3 is a diagnostic and prognostic marker for ovarian epithelial cancer patients based on comprehensive bioinformatics and experiments
por: Chang, Xiaoying, et al.
Publicado: (2021)

Clinical Significance of the HHLA2 Protein in Hepatocellular Carcinoma and the Tumor Microenvironment
por: Luo, Min, et al.
Publicado: (2021)

HHLA2, a member of the B7 family, is expressed in human osteosarcoma and is associated with metastases and worse survival
por: Koirala, Pratistha, et al.
Publicado: (2016)

Overexpression of HHLA2, a member of the B7 family, is associated with worse survival in human colorectal carcinoma
por: Zhu, Ziwen, et al.
Publicado: (2018)

Coexpression of HHLA2 and PD-L1 on Tumor Cells Independently Predicts the Survival of Spinal Chordoma Patients
por: Xia, Chao, et al.
Publicado: (2022)

KIAA0101, a target gene of miR-429, enhances migration and chemoresistance of epithelial ovarian cancer cells
por: Chen, Hong, et al.
Publicado: (2016)

Androgen receptor signaling is required for androgen-sensitive human prostate cancer cell proliferation and survival
por: Yang, Qing, et al.
Publicado: (2005)

Exosomal microRNA-205 is involved in proliferation, migration, invasion, and apoptosis of ovarian cancer cells via regulating VEGFA
por: Wang, Lijun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2o95mtb2v38io0i841keusdpo2