Cargando…

Using historical data to facilitate clinical prevention trials in Alzheimer disease? An analysis of longitudinal MCI (mild cognitive impairment) data sets

BACKGROUND: The Placebo Group Simulation Approach (PGSA) aims at partially replacing randomized placebo-controlled trials (RPCTs), making use of data from historical control groups in order to decrease the needed number of study participants exposed to lengthy placebo treatment. PGSA algorithms to c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Berres, Manfred, Monsch, Andreas U., Spiegel, René
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106156/ https://www.ncbi.nlm.nih.gov/pubmed/33962665 http://dx.doi.org/10.1186/s13195-021-00832-5

Ejemplares similares

Establishing robust cognitive dimensions for characterization and differentiation of patients with Alzheimer's disease, mild cognitive impairment, frontotemporal dementia and depression
por: Beck, Irene R, et al.
Publicado: (2014)

The 12 Years Preceding Mild Cognitive Impairment Due to Alzheimer’s Disease: The Temporal Emergence of Cognitive Decline
por: Mistridis, Panagiota, et al.
Publicado: (2015)

For debate: substituting placebo controls in long-term Alzheimer's prevention trials
por: Spiegel, René, et al.
Publicado: (2011)

Risk Factors for Mild Cognitive Impairment (MCI)
por: Loftus, Andrea Mary
Publicado: (2017)

The Montreal Cognitive Assessment: Normative Data from a German-Speaking Cohort and Comparison with International Normative Samples
por: Thomann, Alessandra E., et al.
Publicado: (2018)

EEG Patterns in Mild Cognitive Impairment (MCI) Patients
por: Baker, Mary, et al.
Publicado: (2008)

Hierarchical Interactions Model for Predicting Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) Conversion
por: Li, Han, et al.
Publicado: (2014)

The Test Your Memory for Mild Cognitive Impairment (TYM-MCI)
por: Brown, Jeremy M, et al.
Publicado: (2017)

The effects of dexmedetomidine on the cognitive function of mild cognitive impairment (MCI) rats
por: Zhou, Qian, et al.
Publicado: (2022)

The Predicted Key Molecules, Functions, and Pathways That Bridge Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)
por: Tao, Ye, et al.
Publicado: (2020)

Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s Disease Dementia (ADD): Using the “Doors and People” Tool to Differentiate between Early aMCI—Late aMCI—Mild ADD Diagnostic Groups
por: Chatzikostopoulos, Athanasios, et al.
Publicado: (2022)

Problems in Classifying Mild Cognitive Impairment (MCI): One or Multiple Syndromes?
por: Díaz-Mardomingo, María del Carmen, et al.
Publicado: (2017)

Screening for Mild Cognitive Impairment: Comparison of “MCI Specific” Screening Instruments
por: O’Caoimh, Rónán, et al.
Publicado: (2016)

Targeted lipidomics distinguishes patient subgroups in mild cognitive impairment (MCI) and late onset Alzheimer's disease (LOAD)
por: Wood, Paul L., et al.
Publicado: (2015)

Brain Resources: How Semantic Cueing Works in Mild Cognitive Impairment due to Alzheimer’s Disease (MCI-AD)
por: Brugnolo, Andrea, et al.
Publicado: (2021)

Structural Brain Imaging Phenotypes of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) Found by Hierarchical Clustering
por: Kärkkäinen, Mikko, et al.
Publicado: (2020)

Considering the base rates of low performance in cognitively healthy older adults improves the accuracy to identify neurocognitive impairment with the Consortium to Establish a Registry for Alzheimer’s Disease-Neuropsychological Assessment Battery (CERAD-NAB)
por: Mistridis, Panagiota, et al.
Publicado: (2015)

Searching for optimal machine learning model to classify mild cognitive impairment (MCI) subtypes using multimodal MRI data
por: Jitsuishi, Tatsuya, et al.
Publicado: (2022)

Diagnosing Mild Cognitive Impairment (MCI) in clinical trials: a systematic review
por: Christa Maree Stephan, Blossom, et al.
Publicado: (2013)

Dysfunctional Incidental Olfaction in Mild Cognitive Impairment (MCI): An Electroencephalography (EEG) Study
por: Walla, Peter, et al.
Publicado: (2011)

Mild cognitive impairment (MCI) and dementia in a sample of adults in the city of Bogotá
por: Pedraza, Olga Lucia, et al.
Publicado: (2017)

Memory deficits for facial identity in patients with amnestic mild cognitive impairment (MCI)
por: Savaskan, Egemen, et al.
Publicado: (2018)

Caregiver burden is increased in Parkinson’s disease with mild cognitive impairment (PD-MCI)
por: Jones, Ann J., et al.
Publicado: (2017)

The epidemiology of mild cognitive impairment (MCI) and Alzheimer’s disease (AD) in community-living seniors: protocol of the MemoVie cohort study, Luxembourg
por: Perquin, Magali, et al.
Publicado: (2012)

Cognitive profiles in Mild Cognitive Impairment (MCI) patients associated with Parkinson's disease and cognitive disorders
por: Pistacchi, Michele, et al.
Publicado: (2015)

Resilience in Mild Cognitive Impairment (MCI): Examining the Level and the Associations of Resilience with Subjective Wellbeing and Negative Affect in Early and Late-Stage MCI
por: Tsormpatzoudi, Styliani Olympia, et al.
Publicado: (2023)

Associations of serum DNA methylation levels of chemokine signaling pathway genes with mild cognitive impairment (MCI) and Alzheimer’s disease (AD)
por: Zou, Ting, et al.
Publicado: (2023)

Occurrence of medical co-morbidity in mild cognitive impairment: implications for generalisation of MCI research
por: Stephan, Blossom C. M., et al.
Publicado: (2011)

The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI)
por: Risacher, Shannon L., et al.
Publicado: (2013)

Episodic and Semantic Autobiographical Memory in Mild Cognitive Impairment (MCI): A Systematic Review
por: Marselli, Giulia, et al.
Publicado: (2023)

The effect of Mild Cognitive Impairment (MCI) on psychological distress among older adults in Ukraine
por: Avery, Jennifer, et al.
Publicado: (2023)

A Pilot Fuzzy System with Virtual Reality for Mild Cognitive Impairment (MCI) Assessment
por: Liu, Cheng-Li, et al.
Publicado: (2023)

Virtual Reality (VR)-Based Environmental Enrichment in Older Adults with Mild Cognitive Impairment (MCI) and Mild Dementia
por: Riaz, Waleed, et al.
Publicado: (2021)

Enhanced diagnostic accuracy for neurocognitive disorders: a revised cut-off approach for the Montreal Cognitive Assessment
por: Thomann, Alessandra E., et al.
Publicado: (2020)

Decreased Retinal Vascular Density in Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI): An Optical Coherence Tomography Angiography (OCTA) Study
por: Wang, Xi, et al.
Publicado: (2021)

In Brief Neuropsychological Assessment, Amnestic Mild Cognitive Impairment (MCI) Is associated with Cerebrospinal Fluid Biomarkers for Cognitive Decline in Contrast to the Prevailing NIA-AA MCI Criterion
por: Hessen, Erik, et al.
Publicado: (2019)

Incidence and predictors of mild cognitive impairment (MCI) within a multi-ethnic Asian populace: a community-based longitudinal study
por: Hussin, Norlela Mohd, et al.
Publicado: (2019)

Parkinson’s Disease–Mild Cognitive Impairment (PD-MCI): A Useful Summary of Update Knowledge
por: Cammisuli, Davide Maria, et al.
Publicado: (2019)

Medical Health Records-Based Mild Cognitive Impairment (MCI) Prediction for Effective Dementia Care
por: Lim, Soo-Jin, et al.
Publicado: (2021)

New Community and Sociohealth Challenges Arising from the Early Diagnosis of Mild Cognitive Impairment (MCI)
por: López, Carolina, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_frc0g7hotrjefmettpihfndk0l