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Fli1 deficiency suppresses RALDH1 activity of dermal dendritic cells and related induction of regulatory T cells: a possible role in scleroderma

BACKGROUND: Aldehyde dehydrogenase 1 family member A1 (RALDH1)-producing dermal dendritic cells (DCs), a conventional DC subset regulating skin fibrosis, are decreased in the involved skin of patients with systemic sclerosis (SSc). In this study, we investigated the contribution of Fli1 deficiency,...

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Detalles Bibliográficos
Autores principales:	Miura, Shunsuke, Watanabe, Yusuke, Saigusa, Ryosuke, Yamashita, Takashi, Nakamura, Kouki, Hirabayashi, Megumi, Miyagawa, Takuya, Yoshizaki, Ayumi, Trojanowska, Maria, Sato, Shinichi, Asano, Yoshihide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106158/ https://www.ncbi.nlm.nih.gov/pubmed/33964960 http://dx.doi.org/10.1186/s13075-021-02520-z

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