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Methotrexate Toxicity: A Simple Solution to a Complex Problem
Methotrexate is a highly effective medication that is the mainstay of treatment for numerous complex dermatological and rheumatological disorders. However, its use requires close monitoring as it has serious side effects that could be fatal if not recognized promptly. Herein, we present an interesti...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106237/ https://www.ncbi.nlm.nih.gov/pubmed/33972915 http://dx.doi.org/10.7759/cureus.14364 |
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author | Asghar, Muhammad Shoaib, Hasan Kang, Woosun Tariq, Irfa Chatterjee, Tulika |
author_facet | Asghar, Muhammad Shoaib, Hasan Kang, Woosun Tariq, Irfa Chatterjee, Tulika |
author_sort | Asghar, Muhammad |
collection | PubMed |
description | Methotrexate is a highly effective medication that is the mainstay of treatment for numerous complex dermatological and rheumatological disorders. However, its use requires close monitoring as it has serious side effects that could be fatal if not recognized promptly. Herein, we present an interesting case of methotrexate toxicity leading to a prolonged hospital stay with resultant increase in health care cost and patient dissatisfaction. It remains of pivotal importance for primary care physicians and hospitalists to be aware of its side effect profile. As such, early recognition of methotrexate toxicity can result in earlier initiation of goal-directed therapies, leading to improved outcomes and shorter hospital stay. Patient education and effective communication between health care providers and the patient are of utmost importance in ensuring patient safety. |
format | Online Article Text |
id | pubmed-8106237 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-81062372021-05-09 Methotrexate Toxicity: A Simple Solution to a Complex Problem Asghar, Muhammad Shoaib, Hasan Kang, Woosun Tariq, Irfa Chatterjee, Tulika Cureus Internal Medicine Methotrexate is a highly effective medication that is the mainstay of treatment for numerous complex dermatological and rheumatological disorders. However, its use requires close monitoring as it has serious side effects that could be fatal if not recognized promptly. Herein, we present an interesting case of methotrexate toxicity leading to a prolonged hospital stay with resultant increase in health care cost and patient dissatisfaction. It remains of pivotal importance for primary care physicians and hospitalists to be aware of its side effect profile. As such, early recognition of methotrexate toxicity can result in earlier initiation of goal-directed therapies, leading to improved outcomes and shorter hospital stay. Patient education and effective communication between health care providers and the patient are of utmost importance in ensuring patient safety. Cureus 2021-04-08 /pmc/articles/PMC8106237/ /pubmed/33972915 http://dx.doi.org/10.7759/cureus.14364 Text en Copyright © 2021, Asghar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Asghar, Muhammad Shoaib, Hasan Kang, Woosun Tariq, Irfa Chatterjee, Tulika Methotrexate Toxicity: A Simple Solution to a Complex Problem |
title | Methotrexate Toxicity: A Simple Solution to a Complex Problem |
title_full | Methotrexate Toxicity: A Simple Solution to a Complex Problem |
title_fullStr | Methotrexate Toxicity: A Simple Solution to a Complex Problem |
title_full_unstemmed | Methotrexate Toxicity: A Simple Solution to a Complex Problem |
title_short | Methotrexate Toxicity: A Simple Solution to a Complex Problem |
title_sort | methotrexate toxicity: a simple solution to a complex problem |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106237/ https://www.ncbi.nlm.nih.gov/pubmed/33972915 http://dx.doi.org/10.7759/cureus.14364 |
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