Divergent low-density lipoprotein receptor (LDLR) linked to low VSV G-dependent viral infectivity and unique serum lipid profile in zebra finches

The low-density lipoprotein receptor (LDLR) is key to cellular cholesterol uptake and is also the main receptor for the vesicular stomatitis virus glycoprotein (VSV G). Here we show that in songbirds LDLR is highly divergent and lacks domains critical for ligand binding and cellular trafficking, inc...

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Detalles Bibliográficos
Autores principales: Velho, Tarciso A. F., Lovell, Peter V., Friedrich, Samantha R., Olson, Christopher R., Miles, Joshua, Mueller, Paul A., Tavori, Hagai, Fazio, Sergio, Lois, Carlos, Mello, Claudio V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106303/
https://www.ncbi.nlm.nih.gov/pubmed/33903244
http://dx.doi.org/10.1073/pnas.2025167118

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