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Study on Hepatotoxicity of Rhubarb Based on Metabolomics and Network Pharmacology

BACKGROUND: Rhubarb, as a traditional Chinese medicine, is the preferred drug for the treatment of stagnation and constipation in clinical practice. It has been reported that rhubarb possesses hepatotoxicity, but its mechanism in vivo is still unclear. METHODS: In this study, the chemical components...

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Detalles Bibliográficos
Autores principales: Li, Shanze, Wang, Yuming, Li, Chunyan, Yang, Na, Yu, Hongxin, Zhou, Wenjie, Chen, Siyu, Yang, Shenshen, Li, Yubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106470/
https://www.ncbi.nlm.nih.gov/pubmed/33976539
http://dx.doi.org/10.2147/DDDT.S301417