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Study on Hepatotoxicity of Rhubarb Based on Metabolomics and Network Pharmacology
BACKGROUND: Rhubarb, as a traditional Chinese medicine, is the preferred drug for the treatment of stagnation and constipation in clinical practice. It has been reported that rhubarb possesses hepatotoxicity, but its mechanism in vivo is still unclear. METHODS: In this study, the chemical components...
Autores principales: | Li, Shanze, Wang, Yuming, Li, Chunyan, Yang, Na, Yu, Hongxin, Zhou, Wenjie, Chen, Siyu, Yang, Shenshen, Li, Yubo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106470/ https://www.ncbi.nlm.nih.gov/pubmed/33976539 http://dx.doi.org/10.2147/DDDT.S301417 |
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