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Parkinson's disease and mitophagy: an emerging role for LRRK2

Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects around 2% of individuals over 60 years old. It is characterised by the loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain, which is thought to account for the major clinical symptom...

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Detalles Bibliográficos
Autores principales: Singh, Francois, Ganley, Ian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106497/
https://www.ncbi.nlm.nih.gov/pubmed/33769432
http://dx.doi.org/10.1042/BST20190236