Cargando…
Mechanisms of repeat-associated non-AUG translation in neurological microsatellite expansion disorders
Repeat-associated non-AUG (RAN) translation was discovered in 2011 in spinocerebellar ataxia type 8 (SCA8) and myotonic dystrophy type 1 (DM1). This non-canonical form of translation occurs in all reading frames from both coding and non-coding regions of sense and antisense transcripts carrying expa...
Autores principales: | Castelli, Lydia M., Huang, Wan-Ping, Lin, Ya-Hui, Chang, Kung-Yao, Hautbergue, Guillaume M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106499/ https://www.ncbi.nlm.nih.gov/pubmed/33729487 http://dx.doi.org/10.1042/BST20200690 |
Ejemplares similares
-
RNA Helicases in Microsatellite Repeat Expansion Disorders and Neurodegeneration
por: Castelli, Lydia M., et al.
Publicado: (2022) -
Repeat Associated Non-AUG Translation (RAN Translation) Dependent on Sequence Downstream of the ATXN2 CAG Repeat
por: Scoles, Daniel R., et al.
Publicado: (2015) -
Prevalence of alternative AUG and non-AUG translation initiators and their regulatory effects across plants
por: Li, Ya-Ru, et al.
Publicado: (2020) -
Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs
por: Das, Michael R., et al.
Publicado: (2023) -
Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats
por: Tseng, Yi-Ju, et al.
Publicado: (2023)