Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma

BACKGROUND: Renal cell carcinoma (RCC) accounts for about 2–3% of all adult malignancies. G protein alpha inhibitory subunit 1 (Gαi1) plays a key role in mediating PI3K-Akt signaling upon activation of receptor tyrosine kinases (RTKs). However, little is known about its expression, regulation and bi...

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Detalles Bibliográficos
Autores principales: Chen, Zhan, Zhang, Yong, Wu, Xiang, Zhang, Ji, Xu, Wei, Shen, Cheng, Zheng, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106533/
https://www.ncbi.nlm.nih.gov/pubmed/33976552
http://dx.doi.org/10.2147/OTT.S298102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106533/
https://www.ncbi.nlm.nih.gov/pubmed/33976552
http://dx.doi.org/10.2147/OTT.S298102

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