Immune cells lacking Y chromosome show dysregulation of autosomal gene expression

Epidemiological investigations show that mosaic loss of chromosome Y (LOY) in leukocytes is associated with earlier mortality and morbidity from many diseases in men. LOY is the most common acquired mutation and is associated with aberrant clonal expansion of cells, yet it remains unclear whether th...

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Detalles Bibliográficos
Autores principales: Dumanski, Jan P., Halvardson, Jonatan, Davies, Hanna, Rychlicka-Buniowska, Edyta, Mattisson, Jonas, Moghadam, Behrooz Torabi, Nagy, Noemi, Węglarczyk, Kazimierz, Bukowska-Strakova, Karolina, Danielsson, Marcus, Olszewski, Paweł, Piotrowski, Arkadiusz, Oerton, Erin, Ambicka, Aleksandra, Przewoźnik, Marcin, Bełch, Łukasz, Grodzicki, Tomasz, Chłosta, Piotr L., Imreh, Stefan, Giedraitis, Vilmantas, Kilander, Lena, Nordlund, Jessica, Ameur, Adam, Gyllensten, Ulf, Johansson, Åsa, Józkowicz, Alicja, Siedlar, Maciej, Klich-Rączka, Alicja, Jaszczyński, Janusz, Enroth, Stefan, Baran, Jarosław, Ingelsson, Martin, Perry, John R. B., Ryś, Janusz, Forsberg, Lars A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106578/
https://www.ncbi.nlm.nih.gov/pubmed/33837451
http://dx.doi.org/10.1007/s00018-021-03822-w

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