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Nature and outcome of malignant goiter: a revisit

INTRODUCTION: the aim of this retrospective study is to review patients with malignant goiter, as regards their nature, demographic characterization, clinical presentation and preoperative histopathological data. METHODS: the study focused on a period of 4 years from December 2015 to January 2019. P...

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Autor principal: Daoud, Mohamed Yasser Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106791/
https://www.ncbi.nlm.nih.gov/pubmed/33995810
http://dx.doi.org/10.11604/pamj.2021.38.204.27503
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author Daoud, Mohamed Yasser Ibrahim
author_facet Daoud, Mohamed Yasser Ibrahim
author_sort Daoud, Mohamed Yasser Ibrahim
collection PubMed
description INTRODUCTION: the aim of this retrospective study is to review patients with malignant goiter, as regards their nature, demographic characterization, clinical presentation and preoperative histopathological data. METHODS: the study focused on a period of 4 years from December 2015 to January 2019. Patients´ demographic data, clinical presentation, Intra-operative findings, Pre and postoperative histopathological staging and grading were all recorded. Postoperative follow up whether early or late were also included. RESULTS: a total of 100% (n = 65) patients underwent surgery. The female to male ratio was found to be 5:1 (48 females and 17 males). Solitary nodule was the main clinical presentation in 80% (n = 52) of cases while 20% (n = 13) were multinodular swellings. Papillary carcinoma was recorded in 80% (n = 52) of patients while in 15.4% (n =10) of patients were having follicular carcinoma. The remaining 4.6% (n = 3) suffered of lymphoma; no medullary or anaplastic tumors were reported. CONCLUSION: thyroid cancer is the most commonly encountered endocrinal malignancy at our institute. Fine Needle Aspiration Cytology (FNAC) showed a high percentage of reliability in diagnosing thyroid cancer among our series. It is recommended to adapt this technique in initial screening of goiter patients in our local setting.
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spelling pubmed-81067912021-05-13 Nature and outcome of malignant goiter: a revisit Daoud, Mohamed Yasser Ibrahim Pan Afr Med J Research INTRODUCTION: the aim of this retrospective study is to review patients with malignant goiter, as regards their nature, demographic characterization, clinical presentation and preoperative histopathological data. METHODS: the study focused on a period of 4 years from December 2015 to January 2019. Patients´ demographic data, clinical presentation, Intra-operative findings, Pre and postoperative histopathological staging and grading were all recorded. Postoperative follow up whether early or late were also included. RESULTS: a total of 100% (n = 65) patients underwent surgery. The female to male ratio was found to be 5:1 (48 females and 17 males). Solitary nodule was the main clinical presentation in 80% (n = 52) of cases while 20% (n = 13) were multinodular swellings. Papillary carcinoma was recorded in 80% (n = 52) of patients while in 15.4% (n =10) of patients were having follicular carcinoma. The remaining 4.6% (n = 3) suffered of lymphoma; no medullary or anaplastic tumors were reported. CONCLUSION: thyroid cancer is the most commonly encountered endocrinal malignancy at our institute. Fine Needle Aspiration Cytology (FNAC) showed a high percentage of reliability in diagnosing thyroid cancer among our series. It is recommended to adapt this technique in initial screening of goiter patients in our local setting. The African Field Epidemiology Network 2021-02-23 /pmc/articles/PMC8106791/ /pubmed/33995810 http://dx.doi.org/10.11604/pamj.2021.38.204.27503 Text en Copyright: Mohamed Yasser Ibrahim Daoud et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Daoud, Mohamed Yasser Ibrahim
Nature and outcome of malignant goiter: a revisit
title Nature and outcome of malignant goiter: a revisit
title_full Nature and outcome of malignant goiter: a revisit
title_fullStr Nature and outcome of malignant goiter: a revisit
title_full_unstemmed Nature and outcome of malignant goiter: a revisit
title_short Nature and outcome of malignant goiter: a revisit
title_sort nature and outcome of malignant goiter: a revisit
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106791/
https://www.ncbi.nlm.nih.gov/pubmed/33995810
http://dx.doi.org/10.11604/pamj.2021.38.204.27503
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