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Effect of mesenchymal stromal cell infusions on lung function in COPD patients with high CRP levels

BACKGROUND: We previously reported a Phase 1/2 randomized placebo-controlled trial of systemic administration of bone marrow-derived allogeneic MSCs (remestemcel-L) in COPD. While safety profile was good, no functional efficacy was observed. However, in view of growing recognition of effects of infl...

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Detalles Bibliográficos
Autores principales: Weiss, Daniel J., Segal, Karen, Casaburi, Richard, Hayes, Jack, Tashkin, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106850/
https://www.ncbi.nlm.nih.gov/pubmed/33964910
http://dx.doi.org/10.1186/s12931-021-01734-8