Novel high‐affinity EGFRvIII‐specific chimeric antigen receptor T cells effectively eliminate human glioblastoma

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OBJECTIVES: The increasing success of Chimeric Antigen Receptor (CAR) T cell therapy in haematological malignancies is reinvigorating its application in many other cancer types and with renewed focus on its application to solid tumors. We present a novel CAR against glioblastoma, an aggressive, mali...

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Detalles Bibliográficos
Autores principales: Abbott, Rebecca C, Verdon, Daniel J, Gracey, Fiona M, Hughes‐Parry, Hannah E, Iliopoulos, Melinda, Watson, Katherine A, Mulazzani, Matthias, Luong, Kylie, D’Arcy, Colleen, Sullivan, Lucy C, Kiefel, Ben R, Cross, Ryan S, Jenkins, Misty R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106904/
https://www.ncbi.nlm.nih.gov/pubmed/33976881
http://dx.doi.org/10.1002/cti2.1283
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