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Attitudes of Indonesian Medical Doctors and Medical Students Toward Genome Editing
PURPOSE: This study aimed to measure the attitudes of Indonesian medical doctors and students toward new technology in genome editing. MATERIALS AND METHODS: Online questionnaires regarding attitudes toward genome editing on health and non-health conditions, both in somatic cells and embryo, were di...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106925/ https://www.ncbi.nlm.nih.gov/pubmed/33981145 http://dx.doi.org/10.2147/JMDH.S303881 |
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author | Izzah, Safira Nur Setyanto, Dimas Hasanatuludhhiyah, Nurina Indiastuti, Danti Nur Nasution, Zamal d’Arqom, Annette |
author_facet | Izzah, Safira Nur Setyanto, Dimas Hasanatuludhhiyah, Nurina Indiastuti, Danti Nur Nasution, Zamal d’Arqom, Annette |
author_sort | Izzah, Safira Nur |
collection | PubMed |
description | PURPOSE: This study aimed to measure the attitudes of Indonesian medical doctors and students toward new technology in genome editing. MATERIALS AND METHODS: Online questionnaires regarding attitudes toward genome editing on health and non-health conditions, both in somatic cells and embryo, were distributed through researcher networks, email and social media specific to medical doctors and students. The data of 1055 valid questionnaires were processed; descriptive and association analyses between sociodemographic factors and attitudes toward genome editing were performed. Email in-depth interview was performed to explore the respondents’ answers. RESULTS: The results showed that Indonesian medical doctors’ and students’ knowledge of genome editing was limited and correlated with gender, place of residence, religion, education, marital status, childbearing and experience abroad. More than half of respondents supported genome editing for the treatment of fatal and debilitating diseases both in somatic cells and embryos, implying their consent to edited gene inheritance. However, this approval decreased when applied to non-health-related aspects, such as physical appearance, intelligence and strength. Factors affecting their attitudes toward genome editing included their status as medical doctors or students, gender, age, education, religion, economic status and place of residence. CONCLUSION: Increasing knowledge and awareness of Indonesian medical doctors and students regarding genome editing is important. Even though its application in health-related matter was supported by a majority of the respondents, discussion from ethical and religious perspectives is necessary to ensure the acceptance. |
format | Online Article Text |
id | pubmed-8106925 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-81069252021-05-11 Attitudes of Indonesian Medical Doctors and Medical Students Toward Genome Editing Izzah, Safira Nur Setyanto, Dimas Hasanatuludhhiyah, Nurina Indiastuti, Danti Nur Nasution, Zamal d’Arqom, Annette J Multidiscip Healthc Original Research PURPOSE: This study aimed to measure the attitudes of Indonesian medical doctors and students toward new technology in genome editing. MATERIALS AND METHODS: Online questionnaires regarding attitudes toward genome editing on health and non-health conditions, both in somatic cells and embryo, were distributed through researcher networks, email and social media specific to medical doctors and students. The data of 1055 valid questionnaires were processed; descriptive and association analyses between sociodemographic factors and attitudes toward genome editing were performed. Email in-depth interview was performed to explore the respondents’ answers. RESULTS: The results showed that Indonesian medical doctors’ and students’ knowledge of genome editing was limited and correlated with gender, place of residence, religion, education, marital status, childbearing and experience abroad. More than half of respondents supported genome editing for the treatment of fatal and debilitating diseases both in somatic cells and embryos, implying their consent to edited gene inheritance. However, this approval decreased when applied to non-health-related aspects, such as physical appearance, intelligence and strength. Factors affecting their attitudes toward genome editing included their status as medical doctors or students, gender, age, education, religion, economic status and place of residence. CONCLUSION: Increasing knowledge and awareness of Indonesian medical doctors and students regarding genome editing is important. Even though its application in health-related matter was supported by a majority of the respondents, discussion from ethical and religious perspectives is necessary to ensure the acceptance. Dove 2021-05-04 /pmc/articles/PMC8106925/ /pubmed/33981145 http://dx.doi.org/10.2147/JMDH.S303881 Text en © 2021 Izzah et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Izzah, Safira Nur Setyanto, Dimas Hasanatuludhhiyah, Nurina Indiastuti, Danti Nur Nasution, Zamal d’Arqom, Annette Attitudes of Indonesian Medical Doctors and Medical Students Toward Genome Editing |
title | Attitudes of Indonesian Medical Doctors and Medical Students Toward Genome Editing |
title_full | Attitudes of Indonesian Medical Doctors and Medical Students Toward Genome Editing |
title_fullStr | Attitudes of Indonesian Medical Doctors and Medical Students Toward Genome Editing |
title_full_unstemmed | Attitudes of Indonesian Medical Doctors and Medical Students Toward Genome Editing |
title_short | Attitudes of Indonesian Medical Doctors and Medical Students Toward Genome Editing |
title_sort | attitudes of indonesian medical doctors and medical students toward genome editing |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106925/ https://www.ncbi.nlm.nih.gov/pubmed/33981145 http://dx.doi.org/10.2147/JMDH.S303881 |
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