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Ribosome quality control activity potentiates vaccinia virus protein synthesis during infection

Viral infection both activates stress signaling pathways and redistributes ribosomes away from host mRNAs to translate viral mRNAs. The intricacies of this ribosome shuffle from host to viral mRNAs are poorly understood. Here, we uncover a role for the ribosome-associated quality control (RQC) facto...

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Detalles Bibliográficos
Autores principales: Sundaramoorthy, Elayanambi, Ryan, Andrew P., Fulzele, Amit, Leonard, Marilyn, Daugherty, Matthew D., Bennett, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8106952/
https://www.ncbi.nlm.nih.gov/pubmed/33912921
http://dx.doi.org/10.1242/jcs.257188