Med1 controls CD8 T cell maintenance through IL‐7R‐mediated cell survival signalling

Under steady‐state conditions, the pool size of peripheral CD8(+) T cells is maintained through turnover and survival. Beyond TCR and IL‐7R signals, the underlying mechanisms are less well understood. In the present study, we found a significant reduction of CD8(+) T cell proportion in spleens but n...

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Detalles Bibliográficos
Autores principales: Lei, Lei, Yang, Xiaofeng, Su, Yanhong, Zheng, Huiqiang, Liu, Jun, Liu, Haiyan, Zou, Yujing, Jiao, Anjun, Wang, Xin, Zhang, Cangang, Zhang, Xingzhe, Zhang, Jiahui, Zhang, Dan, Zhou, Xiaobo, Shi, Lin, Liu, Enqi, Bai, Liang, Sun, Chenming, Zhang, Baojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107092/
https://www.ncbi.nlm.nih.gov/pubmed/33733611
http://dx.doi.org/10.1111/jcmm.16465

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