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Folliculin: A Regulator of Transcription Through AMPK and mTOR Signaling Pathways
Folliculin (FLCN) is a tumor suppressor gene responsible for the inherited Birt-Hogg-Dubé (BHD) syndrome, which affects kidneys, skin and lungs. FLCN is a highly conserved protein that forms a complex with folliculin interacting proteins 1 and 2 (FNIP1/2). Although its sequence does not show homolog...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107286/ https://www.ncbi.nlm.nih.gov/pubmed/33981707 http://dx.doi.org/10.3389/fcell.2021.667311 |