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Overlapping Properties of the Short Membrane-Active Peptide BP100 With (i) Polycationic TAT and (ii) α-helical Magainin Family Peptides

BP100 is a short, designer-made membrane-active peptide with multiple functionalities: antimicrobial, cell-penetrating, and fusogenic. Consisting of five lysines and 6 hydrophobic residues, BP100 was shown to bind to lipid bilayers as an amphipathic α-helix, but its mechanism of action remains uncle...

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Detalles Bibliográficos
Autores principales: Mink, Christian, Strandberg, Erik, Wadhwani, Parvesh, Melo, Manuel N., Reichert, Johannes, Wacker, Irene, Castanho, Miguel A. R. B., Ulrich, Anne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107365/
https://www.ncbi.nlm.nih.gov/pubmed/33981626
http://dx.doi.org/10.3389/fcimb.2021.609542

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