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Small Cell Lung Cancer Transformation as a Resistance Mechanism to Osimertinib in Epidermal Growth Factor Receptor-Mutated Lung Adenocarcinoma: Case Report and Literature Review

Introduction: Small cell lung cancer (SCLC) transformation represents a mechanism of resistance to osimertinib in EGFR-mutated lung adenocarcinoma, which dramatically impacts patients' prognosis due to high refractoriness to conventional treatments. Case Description: We present the case of a pa...

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Detalles Bibliográficos
Autores principales: Leonetti, Alessandro, Minari, Roberta, Mazzaschi, Giulia, Gnetti, Letizia, La Monica, Silvia, Alfieri, Roberta, Campanini, Nicoletta, Verzè, Michela, Olivani, Andrea, Ventura, Luigi, Tiseo, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107466/
https://www.ncbi.nlm.nih.gov/pubmed/33981604
http://dx.doi.org/10.3389/fonc.2021.642190