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Novel Regulatory Factors and Small-Molecule Inhibitors of FGFR4 in Cancer

Fibroblast growth factor receptor 4 (FGFR4) is a tyrosine kinase receptor that is a member of the fibroblast growth factor receptor family and is stimulated by highly regulated ligand binding. Excessive expression of the receptor and its ligand, especially FGF19, occurs in many types of cancer. Abno...

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Detalles Bibliográficos
Autores principales: Liu, Yanan, Wang, Canwei, Li, Jifa, Zhu, Jiandong, Zhao, Chengguang, Xu, Huanhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107720/
https://www.ncbi.nlm.nih.gov/pubmed/33981224
http://dx.doi.org/10.3389/fphar.2021.633453