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Targeting histone deacetylase enhances the therapeutic effect of Erastin-induced ferroptosis in EGFR-activating mutant lung adenocarcinoma

BACKGROUND: Intrinsic or acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) is common, thus strategies for the management of EGFR-TKIs resistance are urgently required. Ferroptosis is a recently discovered form of cell death that has been implicated in tum...

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Detalles Bibliográficos
Autores principales:	Zhang, Tuo, Sun, Beibei, Zhong, Chenxi, Xu, Ke, Wang, Zhexin, Hofman, Paul, Nagano, Tatsuya, Legras, Antoine, Breadner, Daniel, Ricciuti, Biagio, Divisi, Duilio, Schmid, Ralph A., Peng, Ren-Wang, Yang, Haitang, Yao, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107764/ https://www.ncbi.nlm.nih.gov/pubmed/34012798 http://dx.doi.org/10.21037/tlcr-21-303

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