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Preoperative and postoperative radiotherapy (RT) for non-small cell lung cancer: still an open question

Preoperative and postoperative radiotherapy (PORT) with or without chemotherapy has been used in non-small cell lung cancer (NSCLC) for decades. Numerous trials have investigated the potential survival benefit of this strategy, but despite greater knowledge of the disease, considerable technological...

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Autores principales: Van Houtte, Paul, Moretti, Luigi, Charlier, Florian, Roelandts, Martine, Van Gestel, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107767/
https://www.ncbi.nlm.nih.gov/pubmed/34012805
http://dx.doi.org/10.21037/tlcr-20-472
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author Van Houtte, Paul
Moretti, Luigi
Charlier, Florian
Roelandts, Martine
Van Gestel, Dirk
author_facet Van Houtte, Paul
Moretti, Luigi
Charlier, Florian
Roelandts, Martine
Van Gestel, Dirk
author_sort Van Houtte, Paul
collection PubMed
description Preoperative and postoperative radiotherapy (PORT) with or without chemotherapy has been used in non-small cell lung cancer (NSCLC) for decades. Numerous trials have investigated the potential survival benefit of this strategy, but despite greater knowledge of the disease, considerable technological developments in imaging and radiotherapy, and significant progress in surgery, many questions remain unsolved. In this review, we summarize the current knowledge on this problem and discuss issues which still require elucidation.
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spelling pubmed-81077672021-05-18 Preoperative and postoperative radiotherapy (RT) for non-small cell lung cancer: still an open question Van Houtte, Paul Moretti, Luigi Charlier, Florian Roelandts, Martine Van Gestel, Dirk Transl Lung Cancer Res Review Article on Radiotherapy in Thoracic Malignancies Preoperative and postoperative radiotherapy (PORT) with or without chemotherapy has been used in non-small cell lung cancer (NSCLC) for decades. Numerous trials have investigated the potential survival benefit of this strategy, but despite greater knowledge of the disease, considerable technological developments in imaging and radiotherapy, and significant progress in surgery, many questions remain unsolved. In this review, we summarize the current knowledge on this problem and discuss issues which still require elucidation. AME Publishing Company 2021-04 /pmc/articles/PMC8107767/ /pubmed/34012805 http://dx.doi.org/10.21037/tlcr-20-472 Text en 2021 Translational Lung Cancer Research. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Review Article on Radiotherapy in Thoracic Malignancies
Van Houtte, Paul
Moretti, Luigi
Charlier, Florian
Roelandts, Martine
Van Gestel, Dirk
Preoperative and postoperative radiotherapy (RT) for non-small cell lung cancer: still an open question
title Preoperative and postoperative radiotherapy (RT) for non-small cell lung cancer: still an open question
title_full Preoperative and postoperative radiotherapy (RT) for non-small cell lung cancer: still an open question
title_fullStr Preoperative and postoperative radiotherapy (RT) for non-small cell lung cancer: still an open question
title_full_unstemmed Preoperative and postoperative radiotherapy (RT) for non-small cell lung cancer: still an open question
title_short Preoperative and postoperative radiotherapy (RT) for non-small cell lung cancer: still an open question
title_sort preoperative and postoperative radiotherapy (rt) for non-small cell lung cancer: still an open question
topic Review Article on Radiotherapy in Thoracic Malignancies
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107767/
https://www.ncbi.nlm.nih.gov/pubmed/34012805
http://dx.doi.org/10.21037/tlcr-20-472
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