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COVID-19 and hyperglycemia/diabetes

In early studies regarding coronavirus disease 2019 (COVID-19), type 2 diabetes mellitus was considered to contribute substantially to the disease’s inflammatory response. Subsequently, even hyperglycemia, regardless of insulin resistance or diabetes mellitus, was found to be additionally harmful. R...

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Detalles Bibliográficos
Autores principales: Michalakis, Konstantinos, Ilias, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107977/
https://www.ncbi.nlm.nih.gov/pubmed/33995851
http://dx.doi.org/10.4239/wjd.v12.i5.642
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author Michalakis, Konstantinos
Ilias, Ioannis
author_facet Michalakis, Konstantinos
Ilias, Ioannis
author_sort Michalakis, Konstantinos
collection PubMed
description In early studies regarding coronavirus disease 2019 (COVID-19), type 2 diabetes mellitus was considered to contribute substantially to the disease’s inflammatory response. Subsequently, even hyperglycemia, regardless of insulin resistance or diabetes mellitus, was found to be additionally harmful. Recent studies have shown inflammation of the pancreatic β cells in COVID-19, even leading to new onset diabetes mellitus. We hereby summarize core literature on glycemia and COVID-19, and present implicated pathways and mechanisms.
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spelling pubmed-81079772021-05-15 COVID-19 and hyperglycemia/diabetes Michalakis, Konstantinos Ilias, Ioannis World J Diabetes Minireviews In early studies regarding coronavirus disease 2019 (COVID-19), type 2 diabetes mellitus was considered to contribute substantially to the disease’s inflammatory response. Subsequently, even hyperglycemia, regardless of insulin resistance or diabetes mellitus, was found to be additionally harmful. Recent studies have shown inflammation of the pancreatic β cells in COVID-19, even leading to new onset diabetes mellitus. We hereby summarize core literature on glycemia and COVID-19, and present implicated pathways and mechanisms. Baishideng Publishing Group Inc 2021-05-15 2021-05-15 /pmc/articles/PMC8107977/ /pubmed/33995851 http://dx.doi.org/10.4239/wjd.v12.i5.642 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Minireviews
Michalakis, Konstantinos
Ilias, Ioannis
COVID-19 and hyperglycemia/diabetes
title COVID-19 and hyperglycemia/diabetes
title_full COVID-19 and hyperglycemia/diabetes
title_fullStr COVID-19 and hyperglycemia/diabetes
title_full_unstemmed COVID-19 and hyperglycemia/diabetes
title_short COVID-19 and hyperglycemia/diabetes
title_sort covid-19 and hyperglycemia/diabetes
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107977/
https://www.ncbi.nlm.nih.gov/pubmed/33995851
http://dx.doi.org/10.4239/wjd.v12.i5.642
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