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Repurposing metformin for the treatment of gastrointestinal cancer

Diabetes mellitus type 2 and cancer share many risk factors. The pleiotropic insulin-dependent and insulin-independent effects of metformin might inhibit pathways that are frequently amplified in neoplastic tissue. Particularly, modulation of inflammation, metabolism, and cell cycle arrest are poten...

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Detalles Bibliográficos
Autores principales:	Cunha Júnior, Ademar Dantas, Bragagnoli, Arinilda Campos, Costa, Felipe Osório, Carvalheira, José Barreto Campello
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108031/ https://www.ncbi.nlm.nih.gov/pubmed/34007128 http://dx.doi.org/10.3748/wjg.v27.i17.1883

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