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Hemorrhagic infarctive stroke in COVID-19 patients: report of two cases and review of the literature

There is growing evidence in support of ischemic stroke as a manifestation of COVID-19 infection. However, hemorrhagic transformation of ischemic stroke is rare. We present two cases of hemorrhagic infarction as presenting features in COVID-19 patients who did not have traditional cardiovascular ris...

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Autores principales: Owolabi, Lukman Femi, Raafat, Ahmed, Enwere, Okezie Oguamanam, Mustapha, Adekunle F., Adamu, Bappa, AlGhamdi, Mushabab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108187/
https://www.ncbi.nlm.nih.gov/pubmed/34191990
http://dx.doi.org/10.1080/20009666.2021.1883814
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author Owolabi, Lukman Femi
Raafat, Ahmed
Enwere, Okezie Oguamanam
Mustapha, Adekunle F.
Adamu, Bappa
AlGhamdi, Mushabab
author_facet Owolabi, Lukman Femi
Raafat, Ahmed
Enwere, Okezie Oguamanam
Mustapha, Adekunle F.
Adamu, Bappa
AlGhamdi, Mushabab
author_sort Owolabi, Lukman Femi
collection PubMed
description There is growing evidence in support of ischemic stroke as a manifestation of COVID-19 infection. However, hemorrhagic transformation of ischemic stroke is rare. We present two cases of hemorrhagic infarction as presenting features in COVID-19 patients who did not have traditional cardiovascular risk factors for ischemic or hemorrhagic stroke. While the hemorrhagic infarct was from a large artery in one of the patients, the other patient had a small artery related hemorrhagic infarct. We highlighted the possible underlining mechanisms from the literature and the implication of hemorrhagic infarct for routine anticoagulant therapy in patients with COVID −19 related ischemic stroke.
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spelling pubmed-81081872021-05-10 Hemorrhagic infarctive stroke in COVID-19 patients: report of two cases and review of the literature Owolabi, Lukman Femi Raafat, Ahmed Enwere, Okezie Oguamanam Mustapha, Adekunle F. Adamu, Bappa AlGhamdi, Mushabab J Community Hosp Intern Med Perspect Case Report There is growing evidence in support of ischemic stroke as a manifestation of COVID-19 infection. However, hemorrhagic transformation of ischemic stroke is rare. We present two cases of hemorrhagic infarction as presenting features in COVID-19 patients who did not have traditional cardiovascular risk factors for ischemic or hemorrhagic stroke. While the hemorrhagic infarct was from a large artery in one of the patients, the other patient had a small artery related hemorrhagic infarct. We highlighted the possible underlining mechanisms from the literature and the implication of hemorrhagic infarct for routine anticoagulant therapy in patients with COVID −19 related ischemic stroke. Taylor & Francis 2021-05-10 /pmc/articles/PMC8108187/ /pubmed/34191990 http://dx.doi.org/10.1080/20009666.2021.1883814 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of Greater Baltimore Medical Center. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Owolabi, Lukman Femi
Raafat, Ahmed
Enwere, Okezie Oguamanam
Mustapha, Adekunle F.
Adamu, Bappa
AlGhamdi, Mushabab
Hemorrhagic infarctive stroke in COVID-19 patients: report of two cases and review of the literature
title Hemorrhagic infarctive stroke in COVID-19 patients: report of two cases and review of the literature
title_full Hemorrhagic infarctive stroke in COVID-19 patients: report of two cases and review of the literature
title_fullStr Hemorrhagic infarctive stroke in COVID-19 patients: report of two cases and review of the literature
title_full_unstemmed Hemorrhagic infarctive stroke in COVID-19 patients: report of two cases and review of the literature
title_short Hemorrhagic infarctive stroke in COVID-19 patients: report of two cases and review of the literature
title_sort hemorrhagic infarctive stroke in covid-19 patients: report of two cases and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108187/
https://www.ncbi.nlm.nih.gov/pubmed/34191990
http://dx.doi.org/10.1080/20009666.2021.1883814
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