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Spatial distribution of under immunization among children 12–23 months old in Butajira HDSS, southern Ethiopia

BACKGROUND: Immunization is essential to prevent between 2 and 3 million deaths globally each year and it is widely accepted that it is one of the most cost-effective health interventions. Despite all its advantages, immunization in Ethiopia is still far from the target set by the United Nations Sus...

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Autores principales: Ketsela, Admassu, Gebreyesus, Seifu Hagos, Deressa, Wakgari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108332/
https://www.ncbi.nlm.nih.gov/pubmed/33971837
http://dx.doi.org/10.1186/s12887-021-02690-4
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author Ketsela, Admassu
Gebreyesus, Seifu Hagos
Deressa, Wakgari
author_facet Ketsela, Admassu
Gebreyesus, Seifu Hagos
Deressa, Wakgari
author_sort Ketsela, Admassu
collection PubMed
description BACKGROUND: Immunization is essential to prevent between 2 and 3 million deaths globally each year and it is widely accepted that it is one of the most cost-effective health interventions. Despite all its advantages, immunization in Ethiopia is still far from the target set by the United Nations Sustainable Development Goals to achieve universal immunization by all countries in 2030. The 2016 Ethiopian Demographic and Health Survey (EDHS) reported an overall full immunization rate of only 38.3%. The objective of this study was to evaluate the spatial distribution of under immunization in 12 to 23 months old children and further identify the determinants of under immunization clustering in the Butajira Health and Demographic Surveillance Site (HDSS). METHODS: We conducted a community based sectional survey from March to April, 2016 in Butajira HDSS. We collected data on immunization status from a total of 482 children between the age of 12 to 23 months. We randomly selected household and interviewed mothers and /or observed vaccination cards when available to collect data on child’s immunization status. We also collected the geographic location of all villages within the ten Kebeles using a Handheld Global Positioning System (GPS) (Garmin GPSMAP®). We analyzed the spatial distribution of under immunization and clustering using the SatScan® software which employs a purely spatial Bernoulli’s model. We also ran a logistic regression model to help evaluate the causes of clustering. RESULTS: We found that only 22.4% [95% CI: 18.9, 26.4%] of children were fully immunized. This study identified one significant cluster of under immunization among children 12–23 months of age within the Butajira HDSS (relative risk (RR) = 1.24,P < 0·01). We found that children residing in this cluster had more than 1.24 times risk of under immunization compared with children residing outside of the identified cluster. We found significant differences with regard to Maternal Tetanus Toxoid immunization status and place of delivery between cases found within a spatial cluster and cases found outside the cluster. For example, the odds of home delivery is more than two times [AOR 2.21: 95%CI; 1.06, 4.63] among children within an identified spatial cluster than the odds among children found outside the identified cluster. CONCLUSIONS: Under immunization of 12–23 months old children and under immunization with specific vaccines such as Polio, BCG, DPT (1–3) and Measles clustered geographically. Spatial studies could be effective in identifying geographic areas of under immunization for targeted intervention like in this study to gear health education to the specific locality. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-021-02690-4.
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spelling pubmed-81083322021-05-11 Spatial distribution of under immunization among children 12–23 months old in Butajira HDSS, southern Ethiopia Ketsela, Admassu Gebreyesus, Seifu Hagos Deressa, Wakgari BMC Pediatr Research Article BACKGROUND: Immunization is essential to prevent between 2 and 3 million deaths globally each year and it is widely accepted that it is one of the most cost-effective health interventions. Despite all its advantages, immunization in Ethiopia is still far from the target set by the United Nations Sustainable Development Goals to achieve universal immunization by all countries in 2030. The 2016 Ethiopian Demographic and Health Survey (EDHS) reported an overall full immunization rate of only 38.3%. The objective of this study was to evaluate the spatial distribution of under immunization in 12 to 23 months old children and further identify the determinants of under immunization clustering in the Butajira Health and Demographic Surveillance Site (HDSS). METHODS: We conducted a community based sectional survey from March to April, 2016 in Butajira HDSS. We collected data on immunization status from a total of 482 children between the age of 12 to 23 months. We randomly selected household and interviewed mothers and /or observed vaccination cards when available to collect data on child’s immunization status. We also collected the geographic location of all villages within the ten Kebeles using a Handheld Global Positioning System (GPS) (Garmin GPSMAP®). We analyzed the spatial distribution of under immunization and clustering using the SatScan® software which employs a purely spatial Bernoulli’s model. We also ran a logistic regression model to help evaluate the causes of clustering. RESULTS: We found that only 22.4% [95% CI: 18.9, 26.4%] of children were fully immunized. This study identified one significant cluster of under immunization among children 12–23 months of age within the Butajira HDSS (relative risk (RR) = 1.24,P < 0·01). We found that children residing in this cluster had more than 1.24 times risk of under immunization compared with children residing outside of the identified cluster. We found significant differences with regard to Maternal Tetanus Toxoid immunization status and place of delivery between cases found within a spatial cluster and cases found outside the cluster. For example, the odds of home delivery is more than two times [AOR 2.21: 95%CI; 1.06, 4.63] among children within an identified spatial cluster than the odds among children found outside the identified cluster. CONCLUSIONS: Under immunization of 12–23 months old children and under immunization with specific vaccines such as Polio, BCG, DPT (1–3) and Measles clustered geographically. Spatial studies could be effective in identifying geographic areas of under immunization for targeted intervention like in this study to gear health education to the specific locality. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-021-02690-4. BioMed Central 2021-05-10 /pmc/articles/PMC8108332/ /pubmed/33971837 http://dx.doi.org/10.1186/s12887-021-02690-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Ketsela, Admassu
Gebreyesus, Seifu Hagos
Deressa, Wakgari
Spatial distribution of under immunization among children 12–23 months old in Butajira HDSS, southern Ethiopia
title Spatial distribution of under immunization among children 12–23 months old in Butajira HDSS, southern Ethiopia
title_full Spatial distribution of under immunization among children 12–23 months old in Butajira HDSS, southern Ethiopia
title_fullStr Spatial distribution of under immunization among children 12–23 months old in Butajira HDSS, southern Ethiopia
title_full_unstemmed Spatial distribution of under immunization among children 12–23 months old in Butajira HDSS, southern Ethiopia
title_short Spatial distribution of under immunization among children 12–23 months old in Butajira HDSS, southern Ethiopia
title_sort spatial distribution of under immunization among children 12–23 months old in butajira hdss, southern ethiopia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108332/
https://www.ncbi.nlm.nih.gov/pubmed/33971837
http://dx.doi.org/10.1186/s12887-021-02690-4
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