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Human bone marrow-derived, pooled, allogeneic mesenchymal stromal cells manufactured from multiple donors at different times show comparable biological functions in vitro, and in vivo to repair limb ischemia

BACKGROUND: We have previously demonstrated that a pooled population of bone marrow-derived, allogeneic mesenchymal stromal cells (BMMSC), Stempeucel®-1, produced under good manufacturing practices (GMP) conditions, showed clinical efficacy and safety in patients suffering from critical limb ischemi...

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Detalles Bibliográficos
Autores principales: Thej, Charan, Balasubramanian, Sudha, Rengasamy, Mathiyazhagan, Walvekar, Ankita, Swamynathan, Priyanka, Raj, Swathi Sundar, Shahani, Pradnya, Siddikuzzaman, Kolkundkar, Udaykumar, Seetharam, Raviraja N., Gupta, Pawan Kumar, Majumdar, Anish S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108338/
https://www.ncbi.nlm.nih.gov/pubmed/33971964
http://dx.doi.org/10.1186/s13287-021-02330-9