The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients

The extent to which tumors acquire nutrients from dietary sources as opposed to from the breakdown of host tissues is not known. In this issue of BMC Biology, Holland et al. report an approach where food sources with different isotope labeled carbon ratios can be used to answer this question, and fi...

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Autores principales: Abbott, Keene L., Vander Heiden, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108345/
https://www.ncbi.nlm.nih.gov/pubmed/33966629
http://dx.doi.org/10.1186/s12915-021-01027-y
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author Abbott, Keene L.
Vander Heiden, Matthew G.
author_facet Abbott, Keene L.
Vander Heiden, Matthew G.
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collection PubMed
description The extent to which tumors acquire nutrients from dietary sources as opposed to from the breakdown of host tissues is not known. In this issue of BMC Biology, Holland et al. report an approach where food sources with different isotope labeled carbon ratios can be used to answer this question, and find that tumors arising in Drosophila melanogaster procure most of their nutrients from the host.
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spelling pubmed-81083452021-05-11 The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients Abbott, Keene L. Vander Heiden, Matthew G. BMC Biol Commentary The extent to which tumors acquire nutrients from dietary sources as opposed to from the breakdown of host tissues is not known. In this issue of BMC Biology, Holland et al. report an approach where food sources with different isotope labeled carbon ratios can be used to answer this question, and find that tumors arising in Drosophila melanogaster procure most of their nutrients from the host. BioMed Central 2021-05-10 /pmc/articles/PMC8108345/ /pubmed/33966629 http://dx.doi.org/10.1186/s12915-021-01027-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Commentary
Abbott, Keene L.
Vander Heiden, Matthew G.
The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title_full The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title_fullStr The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title_full_unstemmed The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title_short The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title_sort cat-sir is out of the bag: tumors prefer host rather than dietary nutrients
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108345/
https://www.ncbi.nlm.nih.gov/pubmed/33966629
http://dx.doi.org/10.1186/s12915-021-01027-y
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