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Respiratory-tract infections among geriatrics: prevalence and factors associated with the treatment outcomes
BACKGROUND: Geriatric individuals are more susceptible to different infections, especially respiratory-tract infections (RTIs) due to their compromised immune system. Hence, the objectives of the present study were to evaluate the prevalence, medication regimen complexity and factors associated with...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108383/ https://www.ncbi.nlm.nih.gov/pubmed/33910420 http://dx.doi.org/10.1177/1753466620971141 |
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author | Akhtar, Ali Hassali, Mohamed Azmi Ahmad Zainal, Hadzliana Ali, Irfhan Iqbal, Muhammad Shahid Khan, Amer Hayat |
author_facet | Akhtar, Ali Hassali, Mohamed Azmi Ahmad Zainal, Hadzliana Ali, Irfhan Iqbal, Muhammad Shahid Khan, Amer Hayat |
author_sort | Akhtar, Ali |
collection | PubMed |
description | BACKGROUND: Geriatric individuals are more susceptible to different infections, especially respiratory-tract infections (RTIs) due to their compromised immune system. Hence, the objectives of the present study were to evaluate the prevalence, medication regimen complexity and factors associated with the treatment outcomes of different RTIs among geriatrics. METHODS: A retrospective cross-sectional study (5 years) was conducted at the respiratory department, Hospital Pulau Pinang. Patients aged ⩾65 years with confirmed diagnosis of RTI were included in the study. RESULTS: A total of 474 patients were included, and the most prevalent RTIs were community-acquired pneumonia (65.6%) followed by chronic obstructive pulmonary disease (20.7%), bronchitis (8.2%) and hospital-acquired pneumonia (5.5%). Amoxicillin/clavulanate (69.8%), ampicillin/sulbactam (9.1%) and cefuroxime (6.5%) are the most common antibiotics prescribed to treat RTIs among geriatrics. Smoking, alcohol consumption, polypharmacy and presence of other co-morbidities are statistically significant factors associated with treatment outcomes of RTIs among geriatrics. CONCLUSION: Prevalence of community-acquired pneumonia (65.6%) among older patients aged 65 years and older higher than other RTIs. Smoking, alcohol use, presence of polypharmacy and other co-morbidities are important factors associated with the treatment outcomes of RTIs. The reviews of this paper are available via the supplemental material section. |
format | Online Article Text |
id | pubmed-8108383 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-81083832021-05-14 Respiratory-tract infections among geriatrics: prevalence and factors associated with the treatment outcomes Akhtar, Ali Hassali, Mohamed Azmi Ahmad Zainal, Hadzliana Ali, Irfhan Iqbal, Muhammad Shahid Khan, Amer Hayat Ther Adv Respir Dis Original Research BACKGROUND: Geriatric individuals are more susceptible to different infections, especially respiratory-tract infections (RTIs) due to their compromised immune system. Hence, the objectives of the present study were to evaluate the prevalence, medication regimen complexity and factors associated with the treatment outcomes of different RTIs among geriatrics. METHODS: A retrospective cross-sectional study (5 years) was conducted at the respiratory department, Hospital Pulau Pinang. Patients aged ⩾65 years with confirmed diagnosis of RTI were included in the study. RESULTS: A total of 474 patients were included, and the most prevalent RTIs were community-acquired pneumonia (65.6%) followed by chronic obstructive pulmonary disease (20.7%), bronchitis (8.2%) and hospital-acquired pneumonia (5.5%). Amoxicillin/clavulanate (69.8%), ampicillin/sulbactam (9.1%) and cefuroxime (6.5%) are the most common antibiotics prescribed to treat RTIs among geriatrics. Smoking, alcohol consumption, polypharmacy and presence of other co-morbidities are statistically significant factors associated with treatment outcomes of RTIs among geriatrics. CONCLUSION: Prevalence of community-acquired pneumonia (65.6%) among older patients aged 65 years and older higher than other RTIs. Smoking, alcohol use, presence of polypharmacy and other co-morbidities are important factors associated with the treatment outcomes of RTIs. The reviews of this paper are available via the supplemental material section. SAGE Publications 2021-04-28 /pmc/articles/PMC8108383/ /pubmed/33910420 http://dx.doi.org/10.1177/1753466620971141 Text en © The Author(s), 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Research Akhtar, Ali Hassali, Mohamed Azmi Ahmad Zainal, Hadzliana Ali, Irfhan Iqbal, Muhammad Shahid Khan, Amer Hayat Respiratory-tract infections among geriatrics: prevalence and factors associated with the treatment outcomes |
title | Respiratory-tract infections among geriatrics: prevalence and factors associated with the treatment outcomes |
title_full | Respiratory-tract infections among geriatrics: prevalence and factors associated with the treatment outcomes |
title_fullStr | Respiratory-tract infections among geriatrics: prevalence and factors associated with the treatment outcomes |
title_full_unstemmed | Respiratory-tract infections among geriatrics: prevalence and factors associated with the treatment outcomes |
title_short | Respiratory-tract infections among geriatrics: prevalence and factors associated with the treatment outcomes |
title_sort | respiratory-tract infections among geriatrics: prevalence and factors associated with the treatment outcomes |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108383/ https://www.ncbi.nlm.nih.gov/pubmed/33910420 http://dx.doi.org/10.1177/1753466620971141 |
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