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IL-15 mediated expansion of rare durable memory T cells following adoptive cellular therapy

BACKGROUND: Synovial sarcoma (SS) and myxoid/round cell liposarcoma (MRCL) are ideal solid tumors for the development of adoptive cellular therapy (ACT) targeting NY-ESO-1, as a high frequency of tumors homogeneously express this cancer-testes antigen. Data from early phase clinical trials have show...

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Detalles Bibliográficos
Autores principales:	Kohli, Karan, Yao, Lu, Nowicki, Theodore Scott, Zhang, Shihong, Black, Ralph Graeme, Schroeder, Brett A, Farrar, Erik A, Cao, Jianhong, Sloan, Heather, Stief, Dawn, Cranmer, Lee D, Wagner, Michael J, Hawkins, Douglas S, Pillarisetty, Venu G, Ribas, Antoni, Campbell, Jean, Pierce, Robert H, Kim, Edward Y, Jones, Robin L, Riddell, Stanley R, Yee, Cassian, Pollack, Seth M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108691/ https://www.ncbi.nlm.nih.gov/pubmed/33963013 http://dx.doi.org/10.1136/jitc-2020-002232

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