Cargando…

Patient-derived xenograft: a developing tool for screening biomarkers and potential therapeutic targets for human esophageal cancers

Esophageal cancer (EC) represents a human malignancy, diagnosed often at the advanced stage of cancer and resulting in high morbidity and mortality. The development of precision medicine allows for the identification of more personalized therapeutic strategies to improve cancer treatment. By implant...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lan, Tianfeng, Xue, Xia, Dunmall, Louisa Chard, Miao, Jinxin, Wang, Yaohe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109069/ https://www.ncbi.nlm.nih.gov/pubmed/33903283 http://dx.doi.org/10.18632/aging.202934

Ejemplares similares

A Tumor-Targeted Replicating Oncolytic Adenovirus Ad-TD-nsIL12 as a Promising Therapeutic Agent for Human Esophageal Squamous Cell Carcinoma
por: Zhang, Zifang, et al.
Publicado: (2020)

Deoxythymidylate Kinase as a Promising Marker for Predicting Prognosis and Immune Cell Infiltration of Pan-cancer
por: Lan, Tianfeng, et al.
Publicado: (2022)

Characterization of the Intra-tumoral B Cell Immunoglobulin Repertoire Is of Prognostic Value for Esophageal Squamous Cell Carcinoma
por: Wang, Zhizhong, et al.
Publicado: (2022)

Natural products targeting glycolysis in cancer
por: Zhao, Yuanyuan, et al.
Publicado: (2022)

Remodeling the tumor microenvironment by oncolytic viruses: beyond oncolysis of tumor cells for cancer treatment
por: Wang, Lihong, et al.
Publicado: (2022)

Syrian Hamster as an Animal Model for the Study on Infectious Diseases
por: Miao, Jinxin, et al.
Publicado: (2019)

Ferroptosis-Related Genes Are Potential Therapeutic Targets and the Model of These Genes Influences Overall Survival of NSCLC Patients
por: Zhang, Na, et al.
Publicado: (2022)

Syrian hamster as an ideal animal model for evaluation of cancer immunotherapy
por: Jia, Yangyang, et al.
Publicado: (2023)

Optimized Anchor-Modified Peptides Targeting Mutated RAS Are Promising Candidates for Immunotherapy
por: Baleeiro, Renato B., et al.
Publicado: (2022)

An effective therapeutic regime for treatment of glioma using oncolytic vaccinia virus expressing IL-21 in combination with immune checkpoint inhibition
por: Sun, Yijie, et al.
Publicado: (2022)

A systemically deliverable Vaccinia virus with increased capacity for intertumoral and intratumoral spread effectively treats pancreatic cancer
por: Marelli, Giulia, et al.
Publicado: (2021)

A novel vaccinia virus enhances anti-tumor efficacy and promotes a long-term anti-tumor response in a murine model of colorectal cancer
por: Wang, Na, et al.
Publicado: (2020)

Hypoxia-regulated secretion of IL-12 enhances antitumor activity and safety of CD19 CAR-T cells in the treatment of DLBCL
por: Zhou, Wenping, et al.
Publicado: (2023)

Promising xenograft animal model recapitulating the features of human pancreatic cancer
por: Miao, Jin-Xin, et al.
Publicado: (2020)

Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus
por: Ferguson, Mark S., et al.
Publicado: (2020)

MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy
por: Baleeiro, Renato B., et al.
Publicado: (2022)

Redirecting anti-Vaccinia virus T cell immunity for cancer treatment by AAV-mediated delivery of the VV B8R gene
por: Cao, Dujuan, et al.
Publicado: (2022)

Personalized neoantigen viro-immunotherapy platform for triple-negative breast cancer
por: Brito Baleeiro, Renato, et al.
Publicado: (2023)

Therapeutic target biomarkers of patient-derived xenograft models of gastric-type cervical adenocarcinoma
por: Kojima, Yuki, et al.
Publicado: (2023)

Characterization of SHARPIN knockout Syrian hamsters developed using CRISPR/Cas9 system
por: Miao, Jinxin, et al.
Publicado: (2022)

Treatment and Prevention of Lung Cancer Using a Virus-Infected Reprogrammed Somatic Cell-Derived Tumor Cell Vaccination (VIReST) Regime
por: Zhang, Zhe, et al.
Publicado: (2020)

A marker-free system for highly efficient construction of vaccinia virus vectors using CRISPR Cas9
por: Yuan, Ming, et al.
Publicado: (2015)

The two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context
por: Xu, Lingxue, et al.
Publicado: (2022)

Appropriateness of Using Patient-Derived Xenograft Models for Pharmacologic Evaluation of Novel Therapies for Esophageal/Gastro-Esophageal Junction Cancers
por: Dodbiba, Lorin, et al.
Publicado: (2015)

Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers
por: Bradford, James R., et al.
Publicado: (2016)

Tumor Tissue Explant Culture of Patient-Derived Xenograft as Potential Prioritization Tool for Targeted Therapy
por: Ghosh, Susmita, et al.
Publicado: (2019)

Therapeutic implications of transcriptomics in head and neck cancer patient-derived xenografts
por: Lee, Rex H., et al.
Publicado: (2023)

PDXNet portal: patient-derived Xenograft model, data, workflow and tool discovery
por: Koc, Soner, et al.
Publicado: (2022)

Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer
por: van Weerden, W M, et al.
Publicado: (2009)

PPMP, a novel tubulin-depolymerizing agent against esophageal cancer in patient-derived tumor xenografts
por: Sheng, Yuqiao, et al.
Publicado: (2016)

Heterogeneity Analysis of Esophageal Squamous Cell Carcinoma in Cell Lines, Tumor Tissues and Patient-Derived Xenografts
por: Ma, Fayang, et al.
Publicado: (2021)

Novel Tools, Biomarkers, and Disease Entities in Esophageal Disorders
por: Yadlapati, Rena, et al.
Publicado: (2016)

Developing 3D Organoid Raft Cultures from Patient-Derived Xenografts as Rapid Models to Screen Efficacy of Experimental Therapeutics
por: Bajpai, Prachi, et al.
Publicado: (2022)

Non-coding RNAs: new biomarkers and therapeutic targets for esophageal cancer
por: Hou, Xiaobin, et al.
Publicado: (2017)

Novel Immune Checkpoints in Esophageal Cancer: From Biomarkers to Therapeutic Targets
por: Zhou, Xueyin, et al.
Publicado: (2022)

circRNA: A New Biomarker and Therapeutic Target for Esophageal Cancer
por: Shoda, Katsutoshi, et al.
Publicado: (2022)

Tumor xenograft animal models for esophageal squamous cell carcinoma
por: Lee, Nikki P., et al.
Publicado: (2018)

Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics
por: Guilhamon, Paul, et al.
Publicado: (2014)

Patient-derived xenograft mouse models: A high fidelity tool for individualized medicine
por: Xu, Cong, et al.
Publicado: (2019)

Genomic Validation of Endometrial Cancer Patient-Derived Xenograft Models as a Preclinical Tool
por: Villafranca-Magdalena, Beatriz, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_59rt8b8oj7v56m2s52fm5jsnk0