Hepcidin-induced reduction in iron content and PGC-1β expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis

As a necessary trace element, iron is involved in many physiological processes. Clinical and basic studies have found that disturbances in iron metabolism, especially iron overload, might lead to bone loss and even be involved in postmenopausal osteoporosis. Hepcidin is a key regulator of iron homeo...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Wang, Aifei, Shen, Guangsi, Wang, Xiao, Liu, Gongwen, Yang, Fan, Chen, Bin, Wang, Mingyong, Xu, Youjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109081/
https://www.ncbi.nlm.nih.gov/pubmed/33820875
http://dx.doi.org/10.18632/aging.202817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109081/
https://www.ncbi.nlm.nih.gov/pubmed/33820875
http://dx.doi.org/10.18632/aging.202817

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