Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

Dry age-related macular degeneration (AMD) is marked by the accumulation of extracellular and intracellular lipid-rich deposits within and around the retinal pigment epithelium (RPE). Inducing autophagy, a conserved, intracellular degradative pathway, is a potential treatment strategy to prevent dis...

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Detalles Bibliográficos
Autores principales: Zhang, Qitao, Presswalla, Feriel, Ali, Robin R., Zacks, David N., Thompson, Debra A., Miller, Jason ML.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109132/
https://www.ncbi.nlm.nih.gov/pubmed/33872219
http://dx.doi.org/10.18632/aging.202974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109132/
https://www.ncbi.nlm.nih.gov/pubmed/33872219
http://dx.doi.org/10.18632/aging.202974

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