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Long Term Maturation of Human Cortical Organoids Matches Key Early Postnatal Transitions
Human stem cell-derived models provide the promise of accelerating our understanding of brain disorders. But, not knowing whether they possess the ability to mature beyond late mid-fetal stages potentially limits their utility. So, we leveraged a directed differentiation protocol to comprehensively...
Autores principales: | Gordon, Aaron, Yoon, Se-Jin, Tran, Stephen S., Makinson, Christopher D., Park, Jin Young, Andersen, Jimena, Valencia, Alfredo M., Horvath, Steve, Xiao, Xinshu, Huguenard, John R., Pașca, Sergiu P., Geschwind, Daniel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109149/ https://www.ncbi.nlm.nih.gov/pubmed/33619405 http://dx.doi.org/10.1038/s41593-021-00802-y |
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