Mouse Adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge

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The emergence of SARS-CoV-2 has resulted in a worldwide pandemic causing significant damage to public health and the economy. Efforts to understand the mechanisms of COVID-19 disease have been hampered by the lack of robust mouse models. To overcome this barrier, we utilized a reverse genetic system...

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Detalles Bibliográficos
Autores principales: Muruato, Antonio, Vu, Michelle N., Johnson, Bryan A., Davis-Gardner, Meredith E., Vanderheiden, Abigail, Lokugmage, Kumari, Schindewolf, Craig, Crocquet-Valdes, Patricia A., Langsjoen, Rose M., Plante, Jessica A., Plante, Kenneth S., Weaver, Scott C., Debbink, Kari, Routh, Andrew L., Walker, David, Suthar, Mehul S., Xie, Xuping, Shi, Pei-Yong, Menachery, Vineet D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109199/
https://www.ncbi.nlm.nih.gov/pubmed/33972939
http://dx.doi.org/10.1101/2021.05.03.442357
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