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Protective heterologous T cell immunity in COVID-19 induced by MMR and Tdap vaccine antigens

T cells are critical for control of viral infection and effective vaccination. We investigated whether prior Measles-Mumps-Rubella (MMR) or Tetanus-Diphtheria-pertussis (Tdap) vaccination elicit cross-reactive T cells that mitigate COVID-19. Using co-cultures of antigen presenting cells (APC) loaded...

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Detalles Bibliográficos
Autores principales: Mysore, Vijayashree, Cullere, Xavier, Settles, Matthew L., Ji, Xinge, Kattan, Michael W., Desjardins, Michaël, Durbin-Johnson, Blythe, Gilboa, Tal, Baden, Lindsey R., Walt, David R., Lichtman, Andrew, Jehi, Lara, Mayadas, Tanya N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109200/
https://www.ncbi.nlm.nih.gov/pubmed/33972940
http://dx.doi.org/10.1101/2021.05.03.441323