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ORAI1 establishes resistance to SARS-CoV-2 infection by regulating tonic type I interferon signaling
ORAI1 and STIM1 are the critical mediators of store-operated Ca(2+) entry by acting as the pore subunit and an endoplasmic reticulum-resident signaling molecule, respectively. In addition to Ca(2+) signaling, STIM1 is also involved in regulation of a cytosolic nucleic acid sensing pathway. Using ORA...
Autores principales: | Wu, Beibei, Ramaiah, Arunachalam, Garcia, Gustavo, Gwack, Yousang, Arumugaswami, Vaithilingaraja, Srikanth, Sonal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109209/ https://www.ncbi.nlm.nih.gov/pubmed/33972946 http://dx.doi.org/10.1101/2021.05.04.442548 |
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